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Caution really should be exercised when promethazine hydrochloride and codeine phosphate syrup is administered to the nursing girl.
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The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people less than 6 years of age. Concomitant administration of promethazine items with other respiratory depressants has an association with respiratory melancholy, and often Loss of life, in pediatric clients. The Affiliation does in a roundabout way relate to individualized bodyweight-based mostly dosing, which might normally allow safe administration.
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Having said that, getting promethazine with cough and chilly prescription drugs or medicines that contain codeine can increase its sedative or respiratory depressive effects and abuse likely.
Promethazine can cause side effects. Inform your physician if any of those indicators are serious or usually do not go away:
It's not an exhaustive list of attainable drug interactions. You'll want to speak to your health care provider about all the achievable interactions from the drugs you’re having.
Codeine in oral therapeutic dosage does not generally exert big effects around the cardiovascular procedure.
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Codeine: Narcotic analgesics, such as codeine, exert their Main effects about the central nervous method and gastrointestinal tract. The analgesic effects of codeine are as a consequence of its central action; even so, the precise websites of motion have not been determined, and the mechanisms included look like quite complicated.
you should know that this medication could make you drowsy. Do not drive an automobile or run equipment until finally you understand how this medication affects you.
Promethazine hydrochloride injections may cause severe website tissue damage, which include gangrene and necrosis. As of 2009, promethazine carries a next black box warning describing this threat.
Browse the Medication Tutorial if out there from a pharmacist Before you begin having this products and every time you get a refill. Should you have any queries, request your medical doctor or pharmacist.